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nad+
nad+
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Online Men’s Telehealth for Hormone, Metabolic & Preventive Care

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Licensed U.S.Clinicians & Licensed U.S. Pharmacies

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100% Telehealth, Pharmacy-Shipped to Your Door

NAD+ for Cellular Performance & Longevity Support

Prescription-based NAD+ therapy to support energy metabolism, cellular function and recovery.

NAD+ Has Been Shown To

  • Support cellular energy production and normal mitochondrial function
  • Play a role in metabolic processes involved in cellular repair and maintenance
  • Contribute to pathways associated with healthy aging at the cellular level
  • Decline naturally with age, physical stress, and metabolic demand

Designed for Men and Women Who Are Experiencing

  • Age-related declines in energy or cellular resilience
  • Increased physical or cognitive demands that may impact recovery
  • Interest in clinician-guided longevity and metabolic support
  • A desire for a medically supervised approach to cellular health optimization

The Clinical Difference: Human-Use vs. Research-Labeled Products

Your care should be guided by medical standards—not experimentation. When reviewing NAD+ products online, some offerings may be labeled “For Research Purposes Only” or “Not for Human Consumption.” These statements indicate that the product is not intended for clinical use and is not dispensed under medical supervision.

Products labeled for research use are not required to meet the same sterility, quality, or dispensing standards as medications prescribed for human use through licensed clinicians and pharmacies. They are not evaluated as part of a clinician-guided care plan and are not provided pursuant to a valid prescription.

*Statements reflect general scientific observations about NAD+ biology and do not guarantee individual outcomes.

Clinical Context & Considerations for NAD+

NAD+ (Nicotinamide Adenine Dinucleotide) is the coenzyme found in every living cell, responsible for powering your mitochondria.

Cognitive Demand Support
Often considered by individuals with sustained professional or mental workloads who are seeking clinician-guided support for normal cognitive energy during long or demanding days.

Metabolic Re-Engagement
May be considered by individuals resuming physical activity or lifestyle changes following a period of reduced activity, as part of a broader, medically supervised wellness approach.

Travel-Related Physiological Stress
Frequently explored by individuals who travel regularly and are interested in clinician-guided support for general energy regulation during schedule and time-zone changes.

Training & Physical Stress Recovery
Sometimes incorporated during periods of increased physical training or exertion, where cellular energy demands are elevated and recovery support is a consideration under medical supervision.

Structured Weekly Support
Some individuals prefer clinician-directed dosing schedules that align with the start of the week to support consistency within their overall care routine.

This care option is not appropriate for everyone and is offered only when deemed clinically appropriate by a licensed clinician. NAD+ therapy is most commonly considered within the following contexts as part of an individualized, clinician-guided care plan

Prescription Care

1000mg

$249

1000mg total supply • Clinician-authorized • Dispensed by licensed U.S. pharmacies • Shipping included

Prescription Care

2000mg – SAVE $150

$348

2000mg total supply • Clinician-authorized • Dispensed by licensed U.S. pharmacies • Shipping included

Care Experience Ideal Use Application Ingredients

Clinical Evaluation
A licensed clinician reviews your health history and determines whether NAD⁺ therapy is clinically appropriate.

Personalized Care Plan
Treatment protocols are individualized based on medical review and clinical judgment.

Medications & Supplies Included
All prescribed medications and required supplies are included as part of care.

Ongoing Follow-Up Care
Continued clinical oversight to monitor appropriateness and adjust care when indicated.

Secure Clinician Messaging
Direct, ongoing communication with your care team through a secure patient portal.

Status: [RX ONLY] – Clinical Consultation Included

Pharmacy & Medication Standards

We partner with licensed U.S.-based pharmacies that dispense medications intended for human use and prepared in accordance with applicable USP standards. All compounded medications are dispensed pursuant to a valid prescription and are NOT sold or marketed as research-use products.

Prescription-Based, Human-Use Medication

This NAD+ formulation is prescribed by licensed clinicians for human use and dispensed pursuant to a valid prescription, rather than sold as a research-labeled product.

Concentration & Formulation Details

Formulated at 200 mg/mL, provided in a 5 mL multi-dose vial for a total of 1,000 mg NAD+ per vial. 

Designed for At-Home Administration

Provided in a multi-dose vial format intended to support clinician-directed self-administration when appropriate, with instructions supplied as part of care.

Route of Administration
When prescribed, NAD+ may be administered via subcutaneous (SubQ) injection, a route commonly used in clinical care and selected by the prescribing clinician based on individual considerations.

Dosing Guidance
Dosing and frequency are determined solely by a licensed clinician. Protocols may vary based on medical history, clinical assessment, and provider judgment. Patients should follow only the instructions provided by their prescribing clinician.

Post-Administration Sensations
Some individuals report transient sensations following administration, such as mild warmth, pressure, or heightened awareness. Experiences vary and are evaluated in the context of overall clinical care.

Active Ingredient: Nicotinamide Adenine Dinucleotide (NAD+) 200mg per ml.

Inactive Ingredients: Sterile Water for Injection, Bacteriostatic Agent (ensures sterility for multi-use safety).

Benefits of NAD+

Supports Cellular Energy

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NAD+ plays a central role in cellular energy metabolism and is involved in processes that help cells convert nutrients into usable energy.

Supports Mitochondrial Function

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NAD+ is a key coenzyme in mitochondrial pathways that contribute to normal cellular function and metabolic efficiency.

Supports Healthy Aging Pathways

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NAD+ is involved in biological pathways associated with cellular maintenance and age-related metabolic changes.

Supports Cellular Repair Pathways

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NAD+ participates in biological processes associated with cellular maintenance and recovery from metabolic stress.

Supports Cellular Metabolism

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NAD+ is involved in essential metabolic pathways that help cells carry out normal energy-related processes.

Get Started Today

Get Started In 3 Simple Steps

STEP 1

Complete Telehealth Intake

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A licensed U.S. clinician then reviews your medical history and lab work if required to determine eligibility for care.

STEP 2

U.S Pharmacy Delivery

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If prescribed, treatment is dispensed by a licensed U.S. pharmacy & Shipped discreetly to your door.

STEP 3

Ongoing Clinician Guided Care

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Clinicians provide follow-up to review labs and adjust treatment when medically appropriate, supporting individualized care.

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Why Patients Choose TRTBOSS

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Personalized Plans

Care options aligned to your goals, based on individualized clinical review

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Clinician Review + Labs

Start with an online intake. Clinicians may order and review lab work when clinically appropriate.

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Ongoing Monitoring

Follow-ups and adjustments are guided by a licensed clinician based on symptoms, history, and lab results.

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Evidence-informed options

Evidence-Informed Options

Clinician-guided discussion of options for men’s health concerns, based on your evaluation and medical history.

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Care Coordination & Support

Reminders, education, and help navigating next steps—so you know what happens before and after your visit.

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Private Care

Confidential support with secure messaging and account access.

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How NAD+ Supports Cellular Energy & Metabolic Function

Nicotinamide adenine dinucleotide (NAD+) is a naturally occurring coenzyme found in every cell of the body. It plays a central role in cellular energy metabolism and is involved in biochemical pathways that support mitochondrial function, cellular repair processes, and metabolic regulation. NAD+ levels are known to decline with age and increased physiological stress.

Clinician-guided NAD+ therapy is designed to support these foundational cellular processes when clinically appropriate, particularly in individuals interested in longevity-focused care, metabolic support, and recovery under medical supervision.

Unlike oral supplements that rely on digestion and conversion pathways, prescription-based NAD+ therapy is administered as part of a structured, clinician-directed program, allowing for controlled dosing and medical oversight tailored to individual health considerations.

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Switch Confidently From Your Current Provider to TRTBOSS

Better Value. Transparent Pricing. Complete Support.

TRTBOSS vs Other Clinics

Feature

  • Initial Lab work + Consult
  • Monthly Treatment Plans
  • Membership Fee
  • Medications
  • Ongoing Physician Communication
  • Supplies
  • Medication Quality
  • Convenience
  • Ongoing Support
  • Research Grade Compounds
  • Labs
  • Cost to start

Other Clinics

  • $149 – $799
  • $199 – $299/month
  • $19 – $49 per month
  • Up to $99 (plus fees)
  • Up to $199 per consult
  • Up to $70 annually
  • Unknown
  • Commute + waiting rooms
  • Extra fees for follow-ups
  • Unknown
  • Extra
  • 3 to 6 months of service

TRTBOSS TRT

  • $160 FSA / HSA Eligible
  • $169/month FSA / HSA Eligible
  • None
  • Included
  • UNLIMITED through your patient portal
  • Included
  • Licensed US pharmacies
  • 100% online, discreet
  • Unlimited
  • Never
  • Included
  • First + Last
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Trusted.  Legitscript Certified. Confidential.

At TRTBOSS Every step is supported through a clinician-led process with independent, U.S. Licensed clinicians. If prescribed, medications are dispensed and shipped by Licensed U.S LegitScript-certified pharmacies. From expert medical oversight to discreet delivery, We prioritize privacy, secure communications, and clear next steps throughout your experience.

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Customer Reviews

All Reviews

Latest Write a Review

Posted on August 14, 2023

Samantha D.

TRTBOSS has truly changed my life. The process was smooth, the team was supportive, and the results speak for themselves. I feel more energetic, confident, and focused than ever. It’s easily the best decision I’ve made for my health.

Posted on August 14, 2023

Samantha D.

TRTBOSS has truly changed my life. The process was smooth, the team was supportive, and the results speak for themselves. I feel more energetic, confident, and focused than ever. It’s easily the best decision I’ve made for my health.

Posted on August 14, 2023

Samantha D.

TRTBOSS has truly changed my life. The process was smooth, the team was supportive, and the results speak for themselves. I feel more energetic, confident, and focused than ever. It’s easily the best decision I’ve made for my health.

Posted on August 14, 2023

Samantha D.

TRTBOSS has truly changed my life. The process was smooth, the team was supportive, and the results speak for themselves. I feel more energetic, confident, and focused than ever. It’s easily the best decision I’ve made for my health.

Let’s Get Started Load More Reviews

Frequently Asked Questions

Sites selling NAD+ or other peptides without a prescription are legally required to label their product “For Research Only / Not For Human Consumption.” These products are not held to the same safety, sterility, or purity standards as human medication. TRTBOSS requires a prescription because we prioritize your safety, providing only pharmaceutical-grade medication under the guidance of a licensed provider.

When you swallow a pill, stomach acid and digestive enzymes can degrade a significant portion of the active ingredients before they reach your bloodstream. By using the injectable method, you ensure the molecule enters your system intact. You aren’t paying for expensive urine; you are investing in cellular saturation.

Many clients report a lifting of “mental fog” or a boost in alertness within the first one to two weeks*. As you continue the regimen, these benefits often compound. You may not notice the exact moment your energy returns—you’ll simply realize one day that you haven’t felt tired in weeks.
*Individual results may vary.

NAD+ is a molecule your body already produces naturally; we are simply replenishing levels that time has reduced. Our formulation is compounded in regulated US pharmacies to ensure absolute purity and safety standards.

We utilize ultra-thin insulin-style needles for administration. Most clients describe it as a “mosquito bite” sensation.

Medical Citations & Science
The following peer-reviewed science validates the biological mechanism of the NAD+ molecule, not this specific compounded product.

1. The Role of NAD+ in Healthy Aging
Study: Imai, S., & Guarente, L. (2014). NAD+ and sirtuins in aging and disease. Trends in Cell Biology.
Summary: This landmark review highlights how NAD+ levels decline with age and how replenishing them is critical for activating Sirtuins. These proteins are essential for maintaining cellular health and DNA integrity, suggesting NAD+ is a key lever in the longevity conversation.

2. NAD+ and Mitochondrial Health (Energy Production)
Study: Gomes, A. P., et al. (2013). Declining NAD+ induces a pseudohypoxic state disrupting nuclear-mitochondrial communication during aging. Cell.
Summary: Researchers discovered that low NAD+ levels can mimic a state of suffocation for cells, hindering energy production. Restoring NAD+ levels was shown to support mitochondrial function and restore indicators of youthful muscle tissue health.

3. Neuroprotection and Cognitive Support
Study: Fang, E. F., et al. (2019). NAD+ in Aging: Molecular Mechanisms and Translational Implications. Trends in Molecular Medicine.
Summary: This publication explores how NAD+ homeostasis is vital for neuronal health. It suggests that maintaining high NAD+ levels supports neuronal resilience and may offer protection against age-related cognitive decline.

4. Safety of NAD+ Administration
Study: Grant, R., et al. (2019). A Pilot Study Investigating Changes in the Human Plasma and Urine NAD+ Metabolome During a 6 Hour Intravenous Infusion of NAD+. Frontiers in Aging Neuroscience.
Summary: This human clinical study demonstrated that administering NAD+ directly (bypassing the gut) safely and significantly elevates plasma NAD+ levels, validating the safety profile of non-oral administration routes.

Important Safety Information
Prescription Required: This product is available only by prescription from a licensed medical provider. A consultation is required to determine if this therapy is right for you.
FDA Disclaimer: These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Compounding Disclaimer: This product is a compounded medication made in an FDA-monitored 503A/503B pharmacy. It has not been specifically approved by the FDA for safety or efficacy, but is formulated using USP-grade ingredients in compliance with federal and state regulations.

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