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GLP-1GIP + GLYCINE
GLP-1GIP + GLYCINE
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Online Men’s Telehealth for Hormone, Metabolic & Preventive Care

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Licensed U.S.Clinicians & Licensed U.S. Pharmacies

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100% Telehealth, Pharmacy-Shipped to Your Door

Clinician Directed Tirzepatide + Glycine Weight Management from $149 a month

A clinician directed compounded protocol that combines two prescription compounds into a single injectable care plan.

  • Tirzepatide: A dual GLP-1/GIP receptor agonist (“twincretin”) studied for its role in influencing appetite-regulating and glucose-related signaling pathways.
  • Glycine: A naturally occurring amino acid involved in normal metabolic function, protein synthesis, collagen formation, neurotransmitter activity, and cellular processes*. In this compounded protocol, glycine is included as a supportive component as determined by the prescribing clinician.

Program Features

  • Up to 5mg or 15mg Weekly Based on Plan Selection
    Your cost stays the same up to 1mg per week when titrated by your prescriber.
  • 3 Vials Included for Better In-Use Dating
    Instead of one larger vial, eligible bundles are designed to include three separate vials to help support proper beyond-use dating after each vial is first punctured.
  • Clinical Intake Included
    Complete your private online intake so a licensed clinician can review your health history and determine eligibility.
  • Licensed Clinician Review & Prescription Decision
    Your request is reviewed by a qualified medical provider. Prescription issued only if clinically appropriate.
  • Medication + Supplies Included
    Your plan includes the prescribed medication and standard supplies needed for treatment.
  • Shipping Direct to Your Door
    Convenient home delivery from a licensed U.S. pharmacy.
  • Dispensed by Licensed U.S. Pharmacies
    Medications are fulfilled through licensed pharmacy partners following applicable pharmacy standards.
  • 3 Month Prepaid Bundle Savings
    Save with a prepaid 3-month care bundle designed for convenience and cost predictability.
  • Easy Provider Switch Option
    Already using another provider? Switch to TRTBOSS through a streamlined intake and clinical review process.
  • Locked-In Renewal Pricing
    Eligible renewal cycles keep your pricing predictable, helping your plan stay simple and transparent.

The Clinical Difference: Prescription Compounding vs. Non Clinical Products

TRTBOSS DOES NOT source, dispense, or provide “research grade,” research-labeled, or “for research use only” products for patient use. When a clinician determines treatment is appropriate, compounded Tirzepatide + Glycine medications are prescribed based on an individual medical evaluation and prepared by licensed pharmacies operating under applicable compounding regulations.

Status: Prescription [RX] Only – Clinical Consultation Included

Clinical literature evaluating GLP-1 and GLP-1/GIP receptor agonists has described associations with:

  • Appetite-related signaling modulation

  • Satiety-related pathway activity

  • Glucose regulation mechanisms

  • Insulin-sensitivity–related processes

  • Metabolic efficiency markers in appropriate patients

This clinician-guided care approach may be considered for adults experiencing:

  • Persistent appetite regulation despite lifestyle changes

  • Difficulty maintaining consistent nutritional habits

  • Metabolic challenges associated with age or lifestyle factors

  • Energy variability related to glucose fluctuations

Compounded medications are not FDA-approved.

Important Safety Information – GLP-1 & GLP-1/GIP therapies are not appropriate for everyone. Do not use if you have a personal or family history of medullary thyroid carcinoma (MTC) or Multiple Endocrine Neoplasia syndrome type 2 (MEN 2).
Tell your clinician about your full medical history and all medications. Treatment decisions are made by a licensed clinician based on clinical evaluation. Individual results vary.

Prescription Care

Core Plan Subscribe & Save *Save $449*

$149 a month

✔Up to 5mg/week at the same cost ✔Dose titration as directed by your licensed prescriber ✔Private Online Clinical Intake ✔ Licensed clinician review and prescription decision ✔ Medication and supplies included ✔ Shipping directly to your door ✔Dispensed by licensed U.S. pharmacies✔3 months pre-paid bundle savings ✔Easy Switch from your current provider ✔ Locked in pricing on renewal cycles.

Prescription Care

Advanced Plan Subscribe & Save * SAVE $237! *

$220 a month

✔Up to 15mg/week at the same cost ✔Dose titration as directed by your licensed prescriber ✔Private Online Clinical Intake ✔ Licensed clinician review and prescription decision ✔ Medication and supplies included ✔ Shipping directly to your door ✔Dispensed by licensed U.S. pharmacies✔3 months pre-paid bundle savings ✔Easy Switch from your current provider ✔ Locked in pricing on renewal cycles.

Care Experience Ideal Use Application Ingredients

Prescription (Rx) Only
Clinical consultation with a licensed U.S. clinician is included as part of your plan prior to initiation.

What’s Included in Your Care

When clinically appropriate, services may include:

  • Clinical consultations with a licensed U.S. clinician

  • Review of medical history and relevant health information

  • Ongoing follow-up evaluations as determined by the clinician

  • Secure clinician messaging via the patient portal

  • Prescription medications and supplies, when prescribed

  • Discreet, unbranded shipping directly to your door

Medication & Pharmacy Standards

  • Compounded medications, when prescribed, are prepared for human use by licensed U.S. pharmacies

  • Compounding is performed in accordance with applicable USP standards

  • All medications are dispensed pursuant to a valid prescription

  • Compounded medications are not FDA-approved and are not represented as such

  • No medications are marketed, labeled, or distributed as research-use products

Telehealth Convenience & Privacy

  • 100% digital intake and clinician consultations

  • No waiting rooms or in-person visits required

  • Secure patient portal for clinical communication

  • Discreet, unbranded packaging to protect patient privacy

Important Care Context

GLP-1/GIP–based therapies are prescribed only after evaluation by a licensed clinician and may not be appropriate for all individuals. Treatment decisions are based on medical history, clinical assessment, and provider judgment. Individual responses vary. TRTBOSS provides access to clinician-directed telehealth care and care coordination services. No specific outcomes are guaranteed. Fees reflect clinical services, care coordination, and pharmacy fulfillment associated with prescribed therapy and do not guarantee treatment eligibility or prescription issuance. All prescribing decisions are made solely by licensed clinicians.

This clinician-guided care option may be considered for adults who:

  • Meet clinical criteria commonly evaluated by licensed healthcare providers, such as BMI ranges or related metabolic health considerations, as determined during medical review

  • Have previously attempted lifestyle-based approaches and are seeking a medically supervised option

  • Are interested in a prescription-only compounded formulation that includes tirzepatide and L-carnitine, when deemed appropriate by a clinician

  • Prefer individualized evaluation, monitoring, and follow-up within a structured telehealth care environment

  • Understand that all treatment decisions are based on clinical judgment, and that results are not guaranteed

Route:
Injection, as prescribed by a licensed healthcare provider.

Administration:
Medication is self-administered by the patient only after clinician instruction. The specific technique, dosing schedule, and duration of use are determined by the prescribing clinician based on individual medical evaluation.

Frequency:
Administered on a clinician-determined schedule, which may vary based on clinical considerations, patient response, and ongoing monitoring.

Guidance & Monitoring:
Patients receive instructions and ongoing guidance through their care team. Dosage, frequency, or formulation should not be started, stopped, or adjusted without clinician approval.

Important Note: This medication is available by prescription only and is intended for use within a supervised medical care plan. It is not appropriate for everyone, and individual suitability is determined through clinical evaluation.

Active Ingredients (Prescription):

  • Tirzepatide – A dual GLP-1 and GIP receptor agonist prescribed by a licensed healthcare provider based on individual medical evaluation.

  • Glycine: A naturally occurring amino acid involved in normal metabolic function, protein synthesis, collagen formation, neurotransmitter activity, and cellular processes. In this compounded protocol, glycine is included as a supportive component as determined by the prescribing clinician.

Inactive Ingredients:
Inactive ingredients may include sterile water for injection and other pharmaceutical-grade excipients necessary for formulation stability and administration. Exact composition may vary by pharmacy and prescription.

Compounding & Quality Standards:
When prescribed, medications are compounded by licensed U.S. pharmacies operating in accordance with applicable federal and state compounding regulations. Ingredient selection, formulation, and concentration are determined by the dispensing pharmacy pursuant to the clinician’s prescription.

Important Disclosure:
Compounded medications are not FDA-approved. They are prepared by licensed pharmacies for patient use pursuant to a valid prescription when a licensed clinician determines that a compounded formulation is medically appropriate

Mechanisms of Tirzepatide + Glycine

Appetite Pathway Modulation

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GLP-1 and GIP receptor activity influences signaling pathways involved in appetite regulation and satiety perception, as described in clinical literature.

Metabolic Efficiency Signaling

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These incretin-based pathways are studied for their role in coordinating metabolic processes related to nutrient utilization and energy balance.

Glucose Regulation Pathways

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GLP-1/GIP receptor agonists interact with pathways involved in glucose regulation and insulin response in appropriate clinical contexts.

Central & Peripheral Signaling

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Dual GLP-1 and GIP receptor activation engages both central and peripheral signaling mechanisms involved in metabolic regulation.

Neurologic Function Support

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Glycine acts as an inhibitory neurotransmitter in the central nervous system, helping regulate normal nerve signaling and communication.

Energy Metabolism Support

Medication + appetite regulation

Glycine participates in biochemical pathways involved in energy metabolism, amino acid metabolism, and normal cellular function.

Collagen Formation

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Glycine is a major amino acid found in collagen, the structural protein that supports skin, joints, connective tissue, and normal tissue integrity.

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Get Started In 3 Simple Steps

STEP 1

Complete Telehealth Intake

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A licensed U.S. clinician then reviews your medical history and lab work if required to determine eligibility for care.

STEP 2

U.S Pharmacy Delivery

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If prescribed, treatment is dispensed by a licensed U.S. pharmacy & Shipped discreetly to your door.

STEP 3

Ongoing Clinician Guided Care

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Clinicians provide follow-up to review labs and adjust treatment when medically appropriate, supporting individualized care.

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Why Patients Choose TRTBOSS

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Personalized Plans

Care options aligned to your goals, based on individualized clinical review

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Clinician Review + Labs

Start with an online intake. Clinicians may order and review lab work when clinically appropriate.

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Ongoing Monitoring

Follow-ups and adjustments are guided by a licensed clinician based on symptoms, history, and lab results.

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Evidence-informed options

Evidence-Informed Options

Clinician-guided discussion of options for men’s health concerns, based on your evaluation and medical history.

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Care Coordination & Support

Reminders, education, and help navigating next steps—so you know what happens before and after your visit.

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Private Care

Confidential support with secure messaging and account access.

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How Tirzepatide’s Dual-Action Weight Loss Makes It So Effective

Tirzepatide activates both the GLP-1 and GIP hormone pathways. This powerful dual mechanism helps reduce hunger, improve insulin sensitivity, and promote efficient fat loss for those who’ve struggled with traditional diets or medications.

While Semaglutide focuses primarily on appetite suppression, Tirzepatide targets multiple aspects of metabolic health, making it an ideal option for those seeking transformational weight loss without experiencing extreme fatigue or strength loss.

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Switch Confidently From Your Current Provider to TRTBOSS

Better Value. Transparent Pricing. Complete Support.

TRTBOSS vs Other Clinics

Feature

  • Initial Lab work + Consult
  • Monthly Treatment Plans
  • Membership Fee
  • Medications
  • Ongoing Physician Communication
  • Supplies
  • Medication Quality
  • Convenience
  • Ongoing Support
  • Research Grade Compounds
  • Labs

Other Clinics

  • $149 – $799
  • $199 – $299/month
  • $19 – $49 per month
  • Up to $99 (plus fees)
  • Up to $199 per consult
  • Up to $70 annually
  • Unknown
  • Commute + waiting rooms
  • Extra fees for follow-ups
  • Unknown
  • Extra

TRTBOSS TRT

  • $149 FSA / HSA Eligible
  • $149/month FSA / HSA Eligible
  • None
  • Included
  • UNLIMITED through your patient portal
  • Included
  • Licensed US pharmacies
  • 100% online, discreet
  • Unlimited
  • Never
  • Included
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Trusted.  Legitscript Certified. Confidential.

At TRTBOSS Every step is supported through a clinician-led process with independent, U.S. Licensed clinicians. If prescribed, medications are dispensed and shipped by Licensed U.S pharmacies. From expert medical oversight to discreet delivery, We prioritize privacy, secure communications, and clear next steps throughout your experience.

Customer Reviews

All Reviews

Latest Write a Review

Posted on August 14, 2023

Samantha D.

TRTBOSS has truly changed my life. The process was smooth, the team was supportive, and the results speak for themselves. I feel more energetic, confident, and focused than ever. It’s easily the best decision I’ve made for my health.

Posted on August 14, 2023

Samantha D.

TRTBOSS has truly changed my life. The process was smooth, the team was supportive, and the results speak for themselves. I feel more energetic, confident, and focused than ever. It’s easily the best decision I’ve made for my health.

Posted on August 14, 2023

Samantha D.

TRTBOSS has truly changed my life. The process was smooth, the team was supportive, and the results speak for themselves. I feel more energetic, confident, and focused than ever. It’s easily the best decision I’ve made for my health.

Posted on August 14, 2023

Samantha D.

TRTBOSS has truly changed my life. The process was smooth, the team was supportive, and the results speak for themselves. I feel more energetic, confident, and focused than ever. It’s easily the best decision I’ve made for my health.

Let’s Get Started Load More Reviews

Frequently Asked Questions

No. There is no FDA-approved generic for Mounjaro™ or Zepbound™. This is a compounded medication containing Tirzepatide and Glycine.

Glycine is a naturally occurring amino acid involved in normal metabolic function, protein synthesis, collagen formation, neurotransmitter activity, and cellular processes. In this compounded protocol, glycine is included as a supportive component as determined by the prescribing clinician.

Yes. This is a potent medical intervention. A licensed provider must evaluate your health history to ensure this protocol is safe for you.

Clinical Evidence & Publications
-Tirzepatide Efficacy: The SURMOUNT-1 Trial (Jastreboff et al., NEJM) demonstrated that Tirzepatide resulted in substantial weight reduction (up to 20.9%) in adults with obesity.

-Incretin Hormone Mechanism: Seino et al. GIP and GLP-1, the Two Incretin Hormones. Describes GIP and GLP-1 as the two primary incretin hormones released from the intestine after nutrient intake and involved in glucose-dependent insulin secretion. https://pmc.ncbi.nlm.nih.gov/articles/PMC4020673/

– Glycine Mechanism: Multifarious Beneficial Effect of Nonessential Amino Acid, Glycine: A Review. Reviews glycine’s role as a precursor for key metabolites including creatine, glutathione, heme, purines, and porphyrins. https://pmc.ncbi.nlm.nih.gov/articles/PMC5350494/

-Collagen Structure Mechanism:  Proline Precursors and Collagen Synthesis: Biochemical Challenges of Nutrient Supplementation and Wound Healing. Describes collagen as approximately one-third glycine, with glycine appearing at every third amino acid position in the collagen structure. https://pmc.ncbi.nlm.nih.gov/articles/PMC5657141/

-Neurological Signaling Mechanism: National Center for Biotechnology Information (NCBI), Basic Neurochemistry: Glycine Receptors. Describes glycine as a major inhibitory neurotransmitter in the central nervous system, especially the spinal cord. https://www.ncbi.nlm.nih.gov/books/NBK28003/

-Metabolic Pathways Mechanism: Glycine Metabolism and Its Alterations in Obesity and Metabolic Diseases. Reviews glycine’s involvement in biological functions including synthesis of glutathione, purines, creatine, heme-related compounds, and primary bile acids. https://pmc.ncbi.nlm.nih.gov/articles/PMC6627940/

Footer Disclaimer
> Important Safety Information: TRTBOSS facilitates access to medical services provided by independent, licensed physicians. This program utilizes Compounded Tirzepatide combined with Glycine. This is a compounded medication and is not FDA-approved. It is not a generic version of Zepbound™ or Mounjaro™. Compounded medications are prepared by licensed pharmacies to meet individual patient needs and do not undergo FDA review for safety, efficacy, or manufacturing quality. Claims regarding the safety or efficacy of this specific compounded combination have not been evaluated by the FDA. WARNING: Tirzepatide has been associated with thyroid C-cell tumors in animal studies. Do not use if you have a personal or family history of Medullary Thyroid Carcinoma (MTC) or Multiple Endocrine Neoplasia syndrome type 2 (MEN 2). Risks include nausea, pancreatitis, and gallbladder disease. Rx Only.

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